Fig 1.
Flow diagram of study participant’s recruitment at Kokosa District.
Fig 2.
Age and sex distribution of patients affected by leprosy in Kokosa District.
X-axis represents age group and Y-axis represents frequency.
Table 1.
Socio-demographic characteristics of patients affected by leprosy at enrollment, Kokosa district, 2016–2017.
Fig 3.
Leprosy patients enrolled in Kokosa ACD study.
A and B = MB patients.>5 cutaneous lesions; C = PNL, no cutaneous lesions; D = MB (LL) with numerous nodules; E = PB with< 5 cutaneous lesions [(Photos by Tsehaynesh Lema (PI)].
Fig 4.
Clinical characteristics of patients at enrolment.
G0D = grade 0 disabilities, G1D: Grade 1 disabilities, G2D: Grade 2 disabilities, ***9.9% of the patients are PNL cases without cutaneous manifestations.
Fig 5.
Leprosy patients diagnosed with G2D in Kokosa ACD study [(Photos by Tsehaynesh Lema (PI)].
Fig 6.
Level of biomarkers before and after treatment.
a) The levels of anti-PGL-I IgM in the plasma of leprosy patients before and after MDT. b) The levels of anti-PGL-I IgM among HHCs at enrollment and after a year (after the index patients completed MDT, 12 months for MB and 6 months for PB).