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Table 1.

Alfalfa and grass hay nutrient compositions (DM basis)1,2,3.

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Table 1 Expand

Fig 1.

Comparison of whole-blood Se concentrations (mean ± SEM) in weaned beef calves after 3, 6, and 9 weeks in the preconditioning period, and in the feedlot (week 12).

During the 9 week preconditioning period, calves consumed alfalfa hay harvested from a field not fertilized with Se (Control) or from a field fertilized with sodium-selenate (High Se; application rate of 90 g Se/ha; n = 15 calves per group for Control and High Se). Total dietary Se intake during weeks 7 to 9 was 1.09 and 27.45 mg Se/calf per day, respectively for calves in control and High-Se treatment groups. The normal reference interval for whole-blood Se concentrations in beef cattle is 120 to 300 ng/mL.

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Fig 1 Expand

Fig 2.

Comparison of baseline-adjusted BW (kg; mean ± SEM) of weaned beef calves (primarily of Angus breeding and ranging in age from 6 to 9 months at baseline).

During the 9 week preconditioning period, calves consumed alfalfa hay harvested from a field not fertilized with Se (Control) or from a field fertilized with sodium-selenate (High Se; application rate of 90 g Se/ha; n = 15 calves per group for Control and High Se). Body weights at baseline ranged from 264 to 369 kg (328 ± 5 kg, mean ± SEM), and final body weights at the end of the preconditioning period ranged from 288 to 411 kg (366 ± 5 kg, mean ± SEM).

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Fig 3.

Rarefaction analysis of 16S rRNA amplicon sequence variants (ASVs) obtained from nasal swabs after weaning (week 0), at the end of the Se-supplementation preconditioning period (week 9), and in the feedlot (week 12).

During the 9 week preconditioning period, calves consumed alfalfa hay harvested from a field not fertilized with Se (Control) or harvested from a field fertilized with sodium-selenate (High-Se; application rate of 90 g Se/ha; n = 15 calves per group for Control and High-Se).

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Fig 3 Expand

Table 2.

Effect of feeding Se-biofortified hay in a 9-week preconditioning period on nasal microbiome diversity within calves.

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Table 2 Expand

Fig 4.

Principal coordinate analysis of unweighted UniFrac distances obtained from nasal swabs after weaning (week 0), at the end of the Se-supplementation preconditioning period (week 9), and in the feedlot (week 12).

During the 9 week preconditioning period, calves consumed alfalfa hay harvested from a field not fertilized with Se (Control) or harvested from a field fertilized with sodium-selenate (High Se; application rate of 90 g Se/ha; n = 15 calves per group for Control and High Se).

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Fig 4 Expand

Table 3.

Effect of feeding Se-biofortified hay in a 9-week preconditioning period on nasal microbiome diversity within treatment groups.

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Table 3 Expand

Table 4.

Effect of feeding Se-biofortified hay in a 9-week preconditioning period on nasal microbiome diversity across time.

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Fig 5.

Nasal microbiota profiles of healthy calves after weaning (week 0), at the end of the Se-supplementation preconditioning period (week 9), and in the feedlot (week 12).

During the 9 week preconditioning period, calves consumed alfalfa hay harvested from a field not fertilized with Se (Control) or harvested from a field fertilized with sodium-selenate (High Se; application rate of 90 g Se/ha; n = 15 calves per group for Control and High Se).

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Fig 5 Expand

Table 5.

Effect of feeding Se-biofortified hay in a 9-week preconditioning period on number of nasal microbiota phyla.

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Table 6.

Effect of feeding Se-biofortified hay in a 9-week preconditioning period on relative abundance, median % (interquartile range), of the major nasal microbiota phyla*.

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Table 7.

Effect of feeding Se-biofortified hay in a 9-week preconditioning period on the presence, and number of calves harboring per Control (C) and High-Se (Se) treatment groups, of the minor nasal microbiota phyla*.

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Table 8.

Effect of feeding Se-biofortified hay in a 9-week preconditioning period on number of nasal microbiota genera.

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Fig 6.

Nasal Mycoplasmataceae profile of healthy calves after weaning (week 0), at the end of the Se-supplementation preconditioning period (week 9), and in the feedlot (week 12).

During the 9 week preconditioning period, calves consumed alfalfa hay harvested from a field not fertilized with Se (Control) or harvested from a field fertilized with sodium-selenate (High Se; application rate of 90 g Se/ha; n = 15 calves per group for Control and High Se).

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Table 9.

Effect of feeding Se-biofortified hay in a 9-week preconditioning period on number of predicted metabolic pathways in nasal microbiota.

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Table 9 Expand

Fig 7.

Principal coordinate analysis of Bray-Curtis distances of predicted metabolic pathways for healthy calves after weaning (week 0), at the end of the Se-supplementation preconditioning period (week 9), and in the feedlot (week 12).

During the 9 week preconditioning period, calves consumed alfalfa hay harvested from a field not fertilized with Se (Control) or harvested from a field fertilized with sodium-selenate (High Se; application rate of 90 g Se/ha; n = 15 calves per group for Control and High Se).

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