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Table 1.

Demographic data for controls and iNPH patients (shunt responders and non-responders).

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Table 1 Expand

Fig 1.

Example images.

Example FLAIR images from a iNPH patient (a, b) and control (c, d) with corresponding ADC (e-h) and time averaged perfusion raw data (i-l) at the level of the mesencephalon and pons.

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Fig 1 Expand

Fig 2.

Example images after application of ROIs.

FLAIR images at the level of the mesencephalon (a) and pons (b) after application of ROIs (red = posterior ROI, green = middle ROI, yellow = anterior ROI). Corresponding ADC (c, d) and time averaged perfusion raw data (e, f) after alignment and masking of the ROIs. Pale blue voxels (c-f) represent the CSF mask in both the ADC map and perfusion data and dark red voxels (e, f) represent the vessel mask in the perfusion data. Due to corrections for spatial differences and masking, the final ROI in the ADC and perfusion data differ slightly in shape compared to the original ROIs drawn on FLAIR images. Only one of two slices for each location is shown.

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Fig 2 Expand

Table 2.

Apparent diffusion coefficient (ADC) values in controls and iNPH patients given for the composite ROI in the mesencephalon and pons.

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Table 2 Expand

Fig 3.

Correlations between rCBF and iNPH scale score.

Correlations between change in relative cerebral blood flow (rCBF) in the mesencephalon (a) and pons (b) and change in the iNPH scale score after surgery in responders.

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Fig 3 Expand

Table 3.

Relative cerebral blood flow (rCBF) values in controls and iNPH patients given for the composite ROI in the mesencephalon and pons.

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Table 3 Expand