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Fig 1.

Distribution of doubt scores in internet participants (N = 152).

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Fig 2.

Cumulative probability distributions of doubt scores in OCD and non-OCD participants.

OCD (red color; N = 67); non-OCD participants (blue color; N = 27). Participants with OCD exhibited significantly higher doubt scores (rank sum test, p<0.0001).

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Fig 3.

Behavioral task performance in OCD cases and controls.

A) A posterior distribution of group mean drift rate was calculated using HDDM, and indicates the rate of evidence accumulation over 7 different coherences. The most likely group means are plotted; error bars indicate the posterior standard deviation. With higher coherence, higher drift rates were observed for both OCD (red, n = 26) and control (blue, n = 44) subjects. However, at higher levels of coherence, OCD subjects exhibited significantly slower drift rates and reaction times than OCD subjects (q<0.05 for 30%, and 45% coherence; q<0.01 for 70% coherence). B) No significant differences in the posterior distribution of HDDM threshold were observed between OCD and control subjects.

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Fig 4.

Behavioral task performance in participants with high (>60) and low (≤60) doubt scores.

A) A posterior distribution of group mean drift rate was calculated using HDDM, and indicates the rate of evidence accumulation over 8 different coherences. The most likely group means are plotted; error bars indicate the posterior standard deviation. With higher coherence, higher drift rates were observed for both high doubt (orange color, N = 10) and low (black color, N = 36) subjects. However, at higher levels of coherence, high doubt subjects exhibited even faster drift rates and reaction times than low doubt subjects (q<0.01 for 70% coherence). B) No significant differences in the posterior distribution of HDDM threshold were observed between high and low doubt subjects.

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Fig 5.

Relationship between doubt score and drift rate independent of OCD diagnosis.

HDDM was used to calculate the most likely drift rate for each subject with both a doubt score and an OCD diagnosis. Comparisons of all subjects revealed a correlation between doubt score and drift rate at 70% coherence in the no cost condition (v = 3.63 − 0.034DQ; R2 = 0.11; p = 0.024. When subjects with OCD were excluded, control subjects (blue) also exhibited a correlation between doubt score and drift rate at 70% coherence in the no cost condition (v = 4.04 − 0.044DQ; R2 = 0.13; p = 0.038). In OCD subjects alone (red), there was not a significant correlation between doubt score and drift rate OCD subjects: v = 2.66 − 0.016DQ; R2 = 0.04; p = 0.53.

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