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Fig 1.

Patient flow chart.

Out of 470 patients, 312 patients who did not meet inclusion criteria, 8 patients who had inappropriate images and 2 patients who were lost to follow-up were excluded, resulting in a final cohort of 148 patients.

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Fig 2.

Representative cases of CMR.

(1) Cardiac magnetic resonance (CMR) images in midventricular short axis views did not show late gadolinium enhancement (LGE). (2) LGE demonstrated a near-circumferential pattern of midwall LGE (white arrows) in the anterior, septal, inferior, and inferolateral segments at midventricular short axis.

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Table 1.

Patients characteristics.

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Fig 3.

Comparison of cardiac 123I-MIBG scintigraphic findings between the presence or absence of LGE.

The delayed H/M (a) and WR (b) were not significantly different between the presence and absence of LGE.

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Fig 4.

Kaplan-Meier analysis according to LGE on CMR and WR by 123I-MIBG scintigraphy.

(A) DCM patients with WR ≥ 45% (red line) had a worse outcome than those with WR<45% (green line). (B) DCM patients with LGE positive (red line) had a worse outcome than those with LGE negative (green line).

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Fig 5.

Kaplan-Meier analysis of the combination with LGE on CMR and WR by 123I-MIBG scintigraphy.

The WR ≥45%+LGE positive group had the worst prognosis. Of note, the event rate in the WR<45% + LGE positive and WR ≥45%+LGE negative groups were intermediate (p = 0.89).

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Table 2.

Univariate Cox regression analyses for predicting outcome.

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Table 2 Expand

Table 3.

Multivariate Cox regression analyses for predicting outcome.

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