Table 1.
Bacterial probes used in the fluorescent in-situ hybridization (FISH).
Table 2.
Characteristics of Crohn’s disease patients (n = 60) with fecal calprotectin levels indicative of remissive disease (< 100 μg/g) and increased disease activity (> 100 μg/g).
Data are presented as numbers (n (%)), mean ± SD or median [IQR]†.
Fig 1.
The relationship between levels of urinary 24-h 52Cr-EDTA/creatinine excretion and fecal calprotectin.
(A) Distribution of urinary 52Cr-EDTA/creatinine excretion in patients with low (blue, < 100 μg/g) and increased (red, > 100 μg/g) fecal calprotectin levels, shown in boxplots. (B) Urinary 52Cr-EDTA/creatinine excretion significantly correlates with fecal calprotectin levels (ρ = 0.325, P < 0.05), as represented by the red smoothed curve.
Fig 2.
Urinary 24-h excretion of 52Cr-EDTA/creatinine for different subgroups of CD patients according to the Montreal classification of disease localization.
No significant differences were observed between any groups (P > 0.05).
Fig 3.
Correlations of 24-h urinary excretion of 52Cr-EDTA/creatinine with the relative abundances of key bacterial species in the diseased gut, as represented by the red smoothed lines.
(A) A negative correlation (ρ = -0.221, P = 0.092) is observed between the relative abundance (%) of F. prausnitzii and urinary 52Cr-EDTA/creatinine excretion, though this was not statistically significant. (B) A positive correlation (ρ = 0.202, P = 0.126) is observed between the relative abundance (%) of Enterobacteriaceae and urinary 52Cr-EDTA/creatinine excretion, though this correlation was also not statistically significant.