Fig 1.
Comparison of the Biosensor (BS) with spectrophotometry (Spec) a) Scatter plot and b) Bland-Altman plot. Inconsistent results: results with <30% by one method, but not the other; a) rs = 0.7729; p<0.001, n = 152, red lines indicate 30% cut off. b) Mean difference: 0.72 U/gHb, 95% LoA: -4.82 to 3.38 U/gHb (grey shaded area).
Fig 2.
Comparison of the STANDARD G6PD TEST with spectrophotometry a) Scatter plot and b) Bland-Altman Plot. Inconsistent results: results with <30% by one method, but not the other; a) rs = 0.9145; p<0.001, n = 108, red lines indicate 30% cut-off. b) Mean difference: 0.83 U/gHb, 95% LoA: -3.10 to 1.44 U/gHb (grey shaded area).
Fig 3.
Receiver operator curves for the two biosensors at the 30% (a) and 70% (b) threshold activities done in the laboratory. a) p = 0.165, n = 102 b) p = 0.068, n = 102.
Table 1.
Performance in the reference laboratory and optimal cut off of Biosensor and STANDARD G6PD TEST at different thresholds.
Table 2.
Performance and optimal cut-off of SG at different threshold activities in the field.
Fig 4.
Absolute drop in G6PD activity over time under different storage conditions.
Table 3.
Change in G6PD activity between the first measurement by spectrophotometry in the laboratory and after storage at room temperature and 4°C.