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Fig 1.

Health states and pathways used in the decision analysis.

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Table 1.

Congenital heart defects and most common surgical procedures involving use of patches.

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Table 2.

Approach to inform survival in the model.

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Fig 2.

Observed and extrapolated survival.

CHD—congenital heart defects, AS—aortic valve stenosis, VSD—ventricular septal defect, AVSD—atrioventricular septal defect, ToF—tetralogy of Fallot, TGA—transposition of great arteries, CoA—coarctation of the aorta.

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Fig 3.

Observed and extrapolated freedom from reoperation data inputs.

CHD—congenital heart defects, AS—aortic valve stenosis, VSD—ventricular septal defect, AVSD—atrioventricular septal defect, ToF—tetralogy of Fallot, TGA—transposition of great arteries, CoA—coarctation of the aorta.

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Fig 3 Expand

Table 3.

Procedure-specific operation mortality (30-day mortality).

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Table 3 Expand

Table 4.

Clinical parameters.

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Table 5.

Classification of CHD patients into heart failure categories.

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Table 6.

Proxy utility values attached to different age group in patients with CHD diseases.

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Table 7.

Basic Aristotle complexity score and short-term (monthly) disutility’s.

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Table 8.

Resource use data by CHD class.

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Table 9.

Unit costs for resource use and cost of index surgery and reoperations.

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Table 10.

Base-case cost-effectiveness analysis.

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