Fig 1.
CONSORT flow diagram.
Table 1.
Characteristics of FMT donors and recipients (CDI-only, CDI + UC, UC-only).
Table 2.
Pre-FMT UC characteristics.
Fig 2.
Phyla/subphyla comparison of pre-FMT samples of the CDI-only, UC +CDI, and UC-only recipient groups with the donor samples.
The average relative abundance of each of the phyla/subphyla groups is shown for the donor samples and the pre-FMT samples of the CDI-only, CDI + UC and UC-only recipient groups.
Table 3.
Estimated differences (Δ) in Shannon H diversity indices between donor and recipient samples within each group.
Table 4.
Estimated differences (Δ) in Bray Curtis distances for recipient samples relative to donor samples between timepoints for each recipient group (CDI-only, CDI + UC, UC-only).
Fig 3.
Principal coordinate analysis (PCoA) plots for Bray-Curtis distances (beta-diversity).
(A) CDI-only recipient group: Donors (□), pre-FMT recipient (□), 1-wk. post-FMT recipient (□), 3-mos. post-FMT recipient (□); (B) CDI + UC recipient group: Donors (♦), pre-FMT recipient (♦), 1-wk. post-FMT recipient (♦), 3-mos. post-FMT recipient (♦); (C) UC-only recipient group: Donors (●), pre-FMT recipient (●), 1-wk. post-FMT recipient (●), 3-mos. post-FMT recipient (●).
Table 5.
The estimated pre-FMT recipient/donor ratios of the relative abundances of Actinobacteria OTUs for each recipient group.
Table 6.
The estimated pre-FMT recipient/donor ratios of the relative abundances of Bacteroidetes OTUs for each recipient group.
Table 7.
The estimated pre-FMT recipient/donor ratios of the relative abundances of Firmicutes.Ruminococcaceae (Clostridia Group IV) OTUs for each recipient Group.
Table 8.
The estimated ratios (pre-FMT recipient/donor) of the relative abundances of Firmicutes.Lachnospiraceae (Clostridia GroupXIVa) OTUs for each recipient group.
Table 9.
The estimated pre-FMT recipient/donor ratios of the relative abundances of Firmicutes.Bacilli OTUs for each recipient group.
Table 10.
The estimated pre-FMT recipient/donor ratios of the relative abundances of Proteobacteria OTUs for each recipient group.
Table 11.
The estimated pre-FMT recipient/donor ratios of the relative abundances of OTUs in “Other Taxa” for each recipient group.
Table 12.
Estimated differences in log2 (F. Prausnitzii/total bacteria) between donor and recipient samples from each recipient group (CDI-only, CDI + UC, UC-only) and between timepoints.
Table 13.
Post FMT changes in UC characteristics.
The changes were calculated relative to pre-FMT UC characteristics (see Table 2). N.A. means not available because stool sample was not collected or sigmoidoscopy/colonoscopy was not performed at 3 months.