Table 1.
Comparisons of patient characteristics between groups with baseline liver stiffness of ≥1.82 and <1.82 m/s.
Table 2.
Stratified changes in liver stiffness and serum alanine aminotransferase levels from baseline to sustained virologic response visit.
Fig 1.
The paired values of aspartate aminotransferase (AST), alanine aminotransferase (ALT), platelet, liver stiffness, fibrosis-4 (FIB-4) index, and aspartate aminotransferase-to-platelet ratio index (APRI) compared between baseline and sustained virologic response (SVR) visit.
SVR status: yes, n = 219; no, n = 37; *P < 0.05.
Table 3.
Stratified changes in FIB-4 index and aspartate aminotransferase-to-platelet ratio index from baseline to sustained virologic response visit.
Table 4.
Multiple linear regression analysis for declines in liver stiffness, FIB-4 and aspartate aminotransferase-to-platelet ratio index from baseline to sustained virologic response visit.
Table 5.
Multiple logistic regressions for sustained virologic response status.
Fig 2.
Receiver operating characteristic (ROC) curves using baseline liver stiffness (LS), fibrosis-4 (FIB-4) index, and the aspartate aminotransferase-to-platelet ratio index (APRI), and hepatitis C viral (HCV) load to dichotomize sustained virologic response (SVR) (no versus yes).
According to the ROC analysis, the areas under curves were 0.624 (95% confidence interval, 0.514–0.733), 0.655 (0.560–0.751), 0.594 (0.496–0.692), and 0.618 (0.520–0.716) for baseline LS (A), the FIB-4 index (B), APRI (C), and HCV viral load (D), respectively, to dichotomize SVR (no versus yes). The comparison of the AUCs was not significant between the FIB-4 index and LS (P = 0.4231), between the APRI and LS (P = 0.4621), or between the HCV viral load and LS (P = 0.8104).