Table 1.
Baseline socio-demographic variables.
Fig 1.
Plasma concentrations of BDNF, IGF-1 and IGFBP-3 in the alcohol and control groups.
(A) BDNF (pg/mL); (B) IGF-1 (ng/mL); and (C) IGFBP-3 (μg/mL). Bars are the back-transformed means and 95% CI from logarithmic data. (***) p<0.001 denotes significant differences between the alcohol and control groups.
Fig 2.
Correlation analysis between age and plasma concentrations of IGF-1, BDNF and IGFBP-3.
(A) IGF-1 (ng/mL) and age (years) in the total sample; (B) BDNF (pg/mL) and age (years) in the total sample; (C) IGFBP-3 (μg/mL) and age (years) in the total sample; (D) IGF-1 (ng/mL) and IGFBP-3 (μg/mL) in the total sample. Dots represent individual raw values. The Pearson correlation coefficient (r) and p-value are indicated for statistical significance. Note: One outlier value (4.313 pg/mL and 60 years old) was not represented.
Table 2.
Variables associated with AUD and psychiatric comorbidity in the alcohol group.
Fig 3.
Plasma concentrations of BDNF, IGF-1 and IGFBP-3 in the alcohol group according to alcohol-induced liver and pancreas diseases.
(A) BDNF (pg/mL); (B) IGF-1 (ng/mL); and (C) IGFBP-3 (μg/mL) in alcohol group. Bars are the back-transformed means and 95% CI from logarithmic data. (*) p<0.05 denotes significant differences between the disease and no-disease subgroups.