Table 1.
Sequence parameters of FLAIR, DWI, and T2*/SWI of the different scanners.
Fig 1.
Example of the measurement technique of relative ADC values.
The PHE ROI (solid line, right patient side) was transferred to a mirror region (left patient side) and then manually adjusted. Median absolute ADC values of the PHE (solid line), PDR (dotted line), and IPH (not shown) were each divided by median ADC values of the mirror region to calculate the corresponding relative ADC value.
Fig 2.
Two examples of unsegmented (A1 and B1) and segmented (A2 and B2) hyperacute hypertensive right-sided intraparenchymal hemorrhages (IPH) on co-registered axial T2*, fluid-attenuated inversion recovery (FLAIR), diffusion-weighted imaging (DWI), and apparent diffusion coefficient (ADC) images. Example A shows the MRI of a 51 year old male patient 1.5 hours after symptom onset and example B that of a 82 year old male patient in a 3-hour window. The solid line on T2* (A2 and B2) shows the unadjusted IPH ROI and that on FLAIR, DWI, and ADC the adjusted whole lesion ROI (IPH+PHE, IPH ROI is not shown here for the sake of clarity). The dotted line with arrows on DWI and ADC represent the PDR ROI.
Table 2.
Baseline characteristics of all patients and perihematomal rim (PDR)-positive/PDR-negative patients.
Data are given as median and interquartile range (in parenthesis).
Fig 3.
Comparison of relative median ADC values of IPH, PDR, and PHE 0-≤3 hours after symptom onset.
Over time, relative PDR and PHE ADC values rose whereas relative IPH values declined.
Table 3.
Multivariate regression analysis with gender, age, IPH location, time from symptom onset to MRI, NIHSS at admission, and log IPH volume as coefficients.