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Fig 1.

Cohorts for comparing the impact of PCV10 in vaccine-eligible children.

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Fig 2.

Cohorts for comparing the indirect effect of PCV10 in unvaccinated children.

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Table 1.

ICD-10 codes compatible with pneumonia and their distribution in the two reference cohorts from 2003 to 2006 and 2005 to 2008.

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Fig 3.

Monthly incidence rates of pneumonia in children <24 months of age from 2000 through end 2014 with vertical lines showing calendar years and dashed vertical lines showing epidemiological years.

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Fig 4.

Annual pneumonia rates in children less than 2 years of age by epidemic years.

A) all pneumonia outcomes, HDP hospital-diagnosed pneumonia, HTPP hospital-treated primary pneumonia, HDPP hospital-diagnosed pneumococcal pneumonia and empyema; B) HDPP and empyema on different scale.

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Fig 4 Expand

Fig 5.

Annual pneumonia rates in children 2 to 4 years of age by epidemic years.

A) all pneumonia outcomes, HDP hospital-diagnosed pneumonia, HTPP hospital-treated primary pneumonia, HDPP hospital-diagnosed pneumococcal pneumonia and empyema; B) HDPP and empyema on different scale.

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Fig 5 Expand

Table 2.

Rates of pneumonia and the corresponding rate reductions in PCV10 eligible target cohort vs. reference cohorts.

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Table 2 Expand

Fig 6.

The incidence of hospital-treated primary pneumonia (HTPP) by age in vaccine-eligible target cohort compared to reference cohorts before introduction.

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Fig 6 Expand

Table 3.

Rates of pneumonia and the corresponding rate reductions in unvaccinated study cohort vs. reference cohorts.

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Table 3 Expand