Table 1.
Comparison of Background of patients.
Table 2.
List of causative organisms in peritonitis.
Fig 1.
Measurements of sC5b-9, total protein and WBC in PDFs on peritonitis days 1 and 5.
All cases were categorized into gram positives, gram negatives, fungal infection (fungus) and culture negative based on identified causative microorganisms. (A) and (B) show levels of sC5b-9 in peritoneal dialysates (PDFs); (C) and (D) show levels of total protein in PDF; (E) and (F) show white blood cells (WBC) counts in PDF. (A), (C) and (E), day 1 post-onset; (B), (D) and (F), day 5 post-onset. Statistical tests with Kruskal-Wallis test followed by Mann-Whitney U test and Bonferroni correction. *, p<0.05; **, p<0.01.
Fig 2.
PDF levels of adjusted sC5b-9, C3 and C4 and WBC counts after onset of peritonitis.
PDF levels of sC5b-9, C3 and C4 adjusted for total protein on Days 1, 2 and 5 after onset of peritonitis are shown in (A), (C) and (D), respectively. Counts of WBC in PDFs are shown in (B). Gray hatched bar is group 1 and open hatched bar is group 2. ns., not significant. Statistical tests with Mann-Whitney U test and Bonferroni correction.
Fig 3.
Percent change of the PDF levels of adjusted sC5b-9, C3 and C4 after onset of peritonitis.
(A) shows percent change of adjusted levels in PDF of sC5b-9 (A), C3 (B) and C4 (C). (D2-D1)/D1, (D5-D2)/D2 or (D5-D1)/D1 shows changes from days 1 to 2, from days 2 and 5, or from day 1 to 5, respectively. Gray filled hatched bar is group 1 and open hatched bar is group 2. Statistical tests with Mann-Whitney U test and Bonferroni correction. ns., not significant.
Fig 4.
PDF levels of adjusted sC5b-9, C3 and C4 on Day 5 for four categories of microorganisms causing peritonitis.
Levels of adjusted sC5b-9, C3 and C4 in PDF were compared for four categories of microorganisms causing peritonitis on Day 5 after onset of peritonitis. (A) shows levels of adjusted sC5b-9 in PDF, (B) shows levels of adjusted C3 in PDF, and (C) shows levels of adjusted C4 in PDF. Filled bar is group 1 and open bar is group 2. Statistical tests with Mann-Whitney U test and Bonfferoni correction. ns., not significant.
Fig 5.
Levels of sC5b-9, C3 and C4 in PDF and relationship to species of microorganism.
Levels of sC5b-9, C3 and C4 in PDF from patients with peritonitis on day 5 after onset of peritonitis and relationship to species of microorganism were investigated. Staphylococcus aureus includes both methicillin sensitive and methicillin resistant organisms. Gray filled hatched bar is group 1 and open hatched bar is group 2. Statistical tests with Man-Whitney U test and Bonferroni correction. Culture negative: no growth in bacterial culture examination, CNS: coagulase negative Staphylococcus spp., ns: not significance.
Fig 6.
Percent changes of sC5b-9 levels in PDF in relation to causative microorganisms.
PDF from cases were divided into four categories: gram positive bacteria (A), gram negative bacteria (B), fungal infection (C) and culture negative peritonitis (D). Percent changes of sC5b-9 levels were measured in each category. Gray filled hatched bar is group 1 and open hatched bar is group 2. ns: not significant. Statistical tests with Mann-Whitney U test and Bonferroni correction.
Fig 7.
Levels of adjusted sC5b-9, C3 and C4 and WBC counts in PDF of peritonitis.
Levels of adjusted sC5b-9 (A), counts of WBC (B), levels of adjusted C3 (C) and levels of C4 (D) in PDF are significantly different between groups 1 and 2 on day 5 after incidences of peritonitis. Statistical tests with Mann-Whitely U test and Bonferroni correction. Each filled circle is from individual case in group 1 and each open circle is from individual case in group2.
Table 3.
Logistic regression analysis for withdrawal caused by PD-related peritonitis on day 5.