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Fig 1.

Time portraits of (a) minute-wise annotation of the presence (1) and absence (0) of OSA as marked offline by the physician based on polysomnography (PSG) records; (b) and (c) are variations of two significant quantifiers (NPSD and LVM) of HRV signals that are sensitive to the detection of OSA.

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Table 1.

Baseline characteristics of the patients from Apnea-ECG database and St. Vincent’s University Hospital/ University College Dublin Database (UCD database).

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Table 1 Expand

Fig 2.

Evolution pathways of the features, namely NPSD and LVM, of heart rate variability signals for a representative subject during various sleep stages.

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Fig 2 Expand

Fig 3.

Distribution of the feature states in the Laplacian-based coordinate system (V2, V3 and V4) of a representative record.

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Fig 3 Expand

Fig 4.

Scatter plot of prediction versus real observation of time to apnea (a) and run plot showing the predictions of the expected time to sleep apnea onset in a representative patient (b).

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Fig 5.

(a) Prediction performance using randomly selected data from the testing data set for a 1–5 min-ahead prediction with a prediction horizon increment of 1 min and (b) a 1–40 min-ahead prediction with a prediction horizon increment of 5 min.

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Fig 6.

Distribution of the expected time to apnea onset estimated from fT(t|x*) for 1–5 min ahead from left to right.

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Fig 6 Expand

Fig 7.

The waveforms of NPSD, LVM, sleep stage pattern, spectral density of snoring sound, OSA annotation and one-minute ahead prediction of sleep apnea in a subject.

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Fig 7 Expand