Fig 1.
Flowchart of study selection.
Table 1.
Characteristics of studies included in the systematic review.
Fig 2.
Natural history representations.
Only the principal transitions are presented and stratifications were omitted from this figure for simplicity (e.g., heterogeneities related to the exposure to antibiotics). Patients can only be in one of the mutually exclusive health states at a given time (S-E-A-I-R-D: Susceptible-Exposed-Asymptomatic-Infectious-Resistant-Deceased). Two compartments (C and U) are included for interactions between patients and HCWs/visitors. See S3 Appendix for the full description of the natural history assumptions and transmission pathways included in each model.
Table 2.
Relative reduction (%) in CDI outcomes resulting from interventions of CDI prevention and/or control.