Table 1.
Demographic, lifestyle, and clinical characteristics of WHIMS-MRI women by treatment assignment.
Fig 1.
3D surface renderings (upper six images) and representative slices (lower six images) of the ODVBA results on GM volumes comparisons of HT groups < Placebo.
Green indicates the detected significant regions with FWE corrected p < 0.05; regions of hot colors indicate the trends (uncorrected p < 0.05) towards significance characterized by the–log (p) values shown in the colorbar.
Table 2.
The results of GM volume comparisons of HT groups < Placebo. N denotes the number of significant voxels in each anatomical region. t denotes the t value calculated.
Fig 2.
3D surface renderings (upper six images) and representative slices (lower six images) of the ODVBA results on GM volume comparisons of HT groups > Placebo.
Regions of hot colors indicate trends (uncorrected p < 0.05) towards significance characterized by the–log (p) values shown in the colorbar.
Fig 3.
Representative slices of the ODVBA results on WM volume comparisons of (A) HT groups < Placebo, and (B) HT groups > Placebo. Regions of hot colors indicate trends (uncorrected p < 0.05) towards significance characterized by the–log (p) values shown in the colorbar.
Fig 4.
Representative slices of the results of CEE-Alone vs Placebo (light blue) and CEE+MPA vs Placebo (green) on the one standard template.
The detected regions are with threshold of uncorrected p < 0.05. Red represents the overlap of results between the two methods.