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Table 1.

Clinical characteristics of all participants.

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Fig 1.

Experimental procedure.

In each trial, the baseline phase consisted of visual stimuli presenting images of a black dot, and its duration was fixed at 20s. The test phases consisted of self-face and stranger-face visual stimuli. The duration of each test period was 15s. The presentation order of test phases 1 and 2 was alternated for each participant.

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Fig 2.

Placement of NIRS probes.

The probes were placed on the left and right temporal areas centering at T5 and T6 of the International 10–20 system. T5/T6 is indicated by the yellow circle. The distance between the probes was set at 3 cm.

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Fig 3.

The time-course of the average change in oxy-Hb, deoxy-Hb, and total-Hb concentrations.

The time-course of the average change in oxy-Hb, deoxy-Hb, and total-Hb concentrations in the temporal regions of the participants during the presentation of the self-face and stranger-face conditions. Zero on the horizontal axis represents the onset of the test period and the duration of the test period was fixed at 15 s. The area in gray represents the zone that was averaged for statistical analysis.

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Fig 3 Expand

Fig 4.

The mean Z-score during the 12–17 s period.

The mean Z-score during the 12–17 s period after the onset of stimulation in the left and right temporal cortices. The gray bars represent the self-face condition and the white bars represent the stranger-face condition. The error bars represent one SD. The left and right panels indicate the data for the left and right temporal cortices, respectively; the top and bottom panels indicate the data from the AN and control groups, respectively. The statistical significance threshold was set to *P < 0.05.

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Fig 4 Expand