Table 1.
Clinical characteristic of TLE patients.
Fig 1.
The procedure for resting-state MEG data analysis that was used in this study is shown.
Fig 2.
Cortical activation during resting state condition.
(a) The distribution of the average cortical activation during an eyes-closed resting-state condition in 22 control subjects and 16 TLE patients. The activation maps are shown from the top and medial views. The source values were smoothed after re-interpolation (the size of the smoothing kernel = 5). Only the cortical sources which strength is larger than 60% of maximal value are displayed. The current strength for cortical sources shown is color coded with large values represented in white. (b) The p-value maps from the activation comparisons between control subjects and TLE patients are shown. The maps are color coded with significance represented in white and light yellow.
Fig 3.
Difference of functional connectivity between control subjects and TLE patients.
The p-value maps on the sagittal, coronal and axial MR images show the significant differences in mean functional connectivity within the DMN between control subjects and TLE patients in the delta, theta, alpha, beta and gamma bands. Cortical areas encircled by dashed circles indicate cortical areas with significant changes. The maps are color coded with significant values (p < 0.05) denoted in white. The number above the image indicates the slice number.
Fig 4.
Bar plots for the laterality effect on functional connectivity.
(a) The difference in the delta functional connectivity in the left and right MT regions between controls, and left and right TLE patients is shown. (b) There were significant differences in the theta functional connectivity in the left and right ACC regions between controls, and left and right TLE patients. Each error bar represents the standard error of the mean (SEM). * p < 0.05; ** p < 0.01; *** p < 0.001.