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Fig 1.

Overview and design of the study.

This flowchart summarizes our approach in identification of MS related molecular pathways using a combination of two-dimensional gel electrophoresis and mass spectroscopy, with bioinformatics analysis.

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Table 1.

Clinical and demographical data of study group.

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Fig 2.

Representative 2D-PAGE image of each study group including control, CIS, RRMS and PMS.

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Table 2.

Molecular pathways and associated proteins in CIS subtype.

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Table 3.

Molecular pathways and associated proteins in RRMS subtype.

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Table 4.

Molecular pathways and associated proteins in PMS subtype.

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Table 5.

Molecular pathways and associated proteins revealed by CIS subgroup analysis.

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