Figure 1.
A. castellanii STAT protein domains.
(A) The overview of the protein domains. The residues that form phosphotyrosine binding pocket, hydrophobic binding pocket and homodimer binding interface are indicated with arrows. (B) The SH2 domain sequence. The residues that form the phosphotyrosine binding pocket, hydrophobic binding pocket and homodimer binding interface are in red color.
Figure 2.
Alignment of STAT consensus sequences of the structural elements with the A. castellanii STAT functional domains.
“*”, positions with a single, fully conserved residue; “:”, conservation between groups of strongly similar properties; “.”, conservation between groups of weakly similar properties.
Table 1.
Protein sequences similar to A. castellanii STAT (accession number XM_004336169).
Figure 3.
Phylogenetic relationship of the Amoebozoa STAT proteins.
The results were obtained with the aid of MEGA 5.
Figure 4.
Molecular phylogenetic analysis by Maximum Likelihood method of 59 STAT proteins from selected Ophistokonta and Amoebozoa.
The results were obtained using Phylip.