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Table 1.

Differentially expressed genes list.

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Table 1 Expand

Figure 1.

Experimental design.

The flowchart schematizes the experimental steps of the statistical analysis of microarray data.

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Figure 2.

Multidimensional scaling of expression data.

MDS of the expression profiles of ALS and controls shows the correct segregation of samples (see text for details). ALS samples are represented by spheres and controls by cubes.

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Figure 3.

Volcano plot.

This representation of data resulting from microarray analysis compares the size of the fold change with the statistical significance level. x-axis: log2 of FC (fold change of differential gene expression between the ALS patients and controls); y-axis: corresponding p-value resulting from t-test used to measure the significance of the difference between samples in groups.

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Figure 3 Expand

Table 2.

Differentially expressed genes list.

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Table 2 Expand

Table 3.

Discriminant genes list.

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Table 3 Expand

Figure 4.

Gene regulation networks.

Graphical representation of the inter-gene connection existing in the ALS group (a) and controls (b). The correspondence between the numerical labels and the gene ontology annotation is displayed in table 3.

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Table 4.

DAVID functional analysis.

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