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Figure 1.

Data types contributing to characterisation of a clinical entity.

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Figure 2.

Schematic model of the GPRD database.

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Figure 3.

A priori and a posteriori strategies for developing code lists.

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Table 1.

Initial list of indicator markers for early inflammatory arthritis across different clinical domains, based on round-table clinical discussions.

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Figure 4.

Indicator marker groups.

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Table 2.

Prevalence of indicator markers during study period.

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Table 2 Expand

Table 3.

Frequency of combinations of indicator markers.

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Table 4.

Intervals between first indicator marker and diagnosis in RA cases (days).

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Table 4 Expand

Figure 5.

Survival curves for selected indicator markers in the 3

years preceding RA diagnosis, by gender.

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