Table 1.
Clinical Characteristics of Subjects in the Discovery and extended datasets.
Figure 1.
3D score plot of a two-class PLS-DA model of HNF1A versus T2D/GCK; green triangle = HNF1A, red triangle = GCK and blue triangle = T2D.
Q2 = 0.518 using three PLS-components in a valid model (Q2Y = 0.52).
Figure 2.
Scatter diagrams of betaine (A) and glucose adduct (B) ESI+-MS peak intensities in detected samples; grey triangle = control, green triangle = HNF1A, red triangle = GCK and blue triangle = T2D.
Intensity of the signal is plotted as a constant sum normalized value.
Table 2.
Follow up of glucose, amino acid and betaine signals.