Table 1.
Baseline characteristics of cohort with microbiologically proven pandemic influenza A/H1N1 during 2009/2010.
Figure 1.
Range of pH1N1-specific CD4+IFNγ+ and CD8+IFNγ+ T cell frequencies (%) in peripheral blood mononuclear cells of individual patients (n = 22).
Samples taken after natural pH1N1 infection but prior to the onset of the next influenza season. Horizontal line represents median response.
Figure 2.
Representative flow cytometry plots for 3 individual patients.
A) Patient 1: pH1N1 antibody titer of 1∶640, CD4+/IFNγ frequency of 1.78% (positive), and CD8+/IFNγ frequency of 0.57% (positive); B) Patient 2: pH1N1 antibody titer of 1∶80, CD4+/IFNγ frequency of 0.25% (negative), and CD8+/IFNγ frequency of 0.13% (negative); C) Patient 3: Negative serology, CD4+/IFNγ frequency of 0.07% (negative) and CD8+/IFNγ frequency of 0.07% (negative).
Figure 3.
Relationship between CD4+IFNγ T-cell frequency (%) and the humoral response (n = 19).
(R2 = 0.428, P = 0.002).