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Figure 1.

Study design showing the relationship between human leukocyte antigen genes, islet autoantibodies, C-peptide and diabetic retinopathy.

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Figure 2.

Flow diagram of study participants.

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Table 1.

Characteristics of participants at the clinical onset of type 1 diabetes mellitusa and reference panel of matched controlsb by HLA genotype.

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Table 2.

Characteristics of participants at the clinical onset of type 1 diabetes mellitusa by islet autoantibody status.

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Table 3.

Characteristics of participants 15 years after the clinical onset of type 1 diabetes mellitusa by HLA genotype.

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Table 3 Expand

Table 4.

Characteristics of participants 15 years after the clinical onset of type 1 diabetes mellitusa by islet autoantibody status.

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Table 5.

Grade of retinopathy by eye from 235 participants with fundus photos.

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Table 6.

Results of relative risk regression analyses for diabetic retinopathy, primary analysis.

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Table 7.

Results of relative risk regression analyses for diabetic retinopathy, secondary analyses.

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