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The applicability of non-invasive methods for assessing liver fibrosis in hemodialysis patients with chronic hepatitis C

Fig 1

The operating characteristic curves (ROC) of APRI and FIB-4 for the prediction of patients with significant hepatic fibrosis (≥F2), advanced hepatic fibrosis (≥F3), and cirrhosis (F4) in dialysis patient with chronic hepatitis C.

(A) AUC of APRI (0.70, 95% CI: 0.60 to 0.80; P = 0.004) and that of FIB-4 (0.68, 95% CI: 0.58 to 0.78; P = 0.01) for patients with a fibrosis stage of F2 or more. (B) AUC of APRI (0.73, 95% CI: 0.63 to 0.82; P = 0.002) and that of FIB-4 (0.75, 95% CI: 0.66 to 0.85; P value < 0.001) for patient with a fibrosis stage of F3 or more. (C) AUC of APRI (0.76, 95% CI: 0.66 to 0.86; P<0.001) and that of FIB-4 (0.77, 95% CI: 0.67 to 0.88; P value < 0.001) patients with a fibrosis stage of F4.

Fig 1

doi: https://doi.org/10.1371/journal.pone.0242601.g001