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Chronic oral application of a periodontal pathogen results in brain inflammation, neurodegeneration and amyloid beta production in wild type mice

Fig 3

Pg/gingipain is present intracellularly in astrocytes, microglia and neurons in the hippocampus of experimental mice.

Green: astrocytes (top panels), microglia (middle panels), and neurons (bottom panels). Red: Pg/gingipain. Blue: DAPI. Representative of N = 4 (GFAP), 3 (Iba1) and 4 (NeuN) experimental mice.

Fig 3

doi: https://doi.org/10.1371/journal.pone.0204941.g003