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Kinomics toolbox—A web platform for analysis and viewing of kinomic peptide array data

Fig 4

Measurement reproducibility for kinetic parameterization.

In panels A-C, kinetic curves created by images series of varying exposure times (vi,e) are compared to the more robust vi. The data presented is 144 peptides for all 12 samples discussed in Methods. Panel A is a 10 ms exposure time and has a Pearson's r = 0.9981 and a Spearman's ρ = 0.9097. Panel B is a 50 ms exposure time and has a Pearson's r = 0.9989 and a Spearman's ρ = 0.9920. Panel C is a 200 ms exposure time and has a Pearson's r = 0.9807 and a Spearman's ρ = 0.9995. Panels D compares ls(vi,50 (s), vi,50,b(b)) to ls(vi (s), vi,·,b(b)) and has a Pearson's r = 0.9887 and a Spearman's ρ = 0.9279. Panels E compares to and has a Pearson's r = 0.9941; Spearman's ρ = 0.9681. These figures and all similar variations can be further investigated and explored at http://bit.kinomecore.com/?fig4a for b and at http://bit.kinomecore.com/?fig4b for .

Fig 4

doi: https://doi.org/10.1371/journal.pone.0202139.g004