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Oral edible plant vaccine containing hypoallergen of American cockroach major allergen Per a 2 prevents roach-allergic asthma in a murine model

Fig 5

Effect of plant vaccine on airway hyperresponsiveness in rPer a 2-challenged mice.

Mean enhanced pause (Penh) values were evaluated at indicated doses of methacholine (Mch) in the four groups (n = 5–6 per group). *p<0.05 by one-way analysis of variance with the Bonferroni multiple range test.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0201281.g005