Oral edible plant vaccine containing hypoallergen of American cockroach major allergen Per a 2 prevents roach-allergic asthma in a murine model
(A) Per a 2-specific IgE antibodies in the sera at the indicated weeks. (B) Serum levels of Per a 2-specific IgE, IgG 1 and IgG2a among groups at week 9 determined by ELISA. Results are mean±SEM of 5–6 mice from each group. *p<0.05; ***p<0.001 by one-way analysis of variance with the Bonferroni multiple range test.