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Probing structural changes in single enveloped virus particles using nano-infrared spectroscopic imaging

Fig 2

Spatial evolution of virus particles when acidity changed from pH 7 to pH 5.

Topography (black & white), and near-field amplitude (A3) and phase (φ3) images of four virus particles at pH 7 (a) and pH 5 (b) taken at 1225 and 1665 cm-1. Scale bar 100 nm.

Fig 2