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Microbiota epitope similarity either dampens or enhances the immunogenicity of disease-associated antigenic epitopes

Fig 1

HLA class II restricted T cell epitopes vary in similarity to human microbiome sequences.

Epitope (black) and non-epitope (red) maximum BLOSUM score per individual peptide are shown for the Aspergillus (A) and Gluten (B) epitope categories. Median ± interquartile range are shown for each distribution.

Fig 1