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Efficacy and synergy of live-attenuated and inactivated influenza vaccines in young chickens

Fig 3

Mucosal antibody responses in tears of 2 week-old chickens.

Birds were vaccinated at 1 day of age and tear samples collected at 14 days post-vaccination for antibody detection. (A) Total antibody against NP antigen. (B) Influenza virus-specific IgG. (C) Influenza virus-specific IgA. The NPRI and OD values shown on the y-axis were normalized to the mean value of the unvaccinated group. The asterisks indicate significant differences compared with unvaccinated group (*p<0.05, **p<0.01, and *** p<0.001).

Fig 3

doi: https://doi.org/10.1371/journal.pone.0195285.g003