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Combined use of protein biomarkers and network analysis unveils deregulated regulatory circuits in Duchenne muscular dystrophy

Fig 1

Study workflow.

Proteomics data produced with SOMAscan technology were analyzed using a rank-based classification algorithm. We obtained two set of proteins (biomarker panels) useful for subject classification and disease characterization. The longer biomarker panel was used as input for network-based analysis.

Fig 1