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Development of improved therapeutic mesothelin-based vaccines for pancreatic cancer

Fig 8

Pretreatment and intratumoral injections.

(A) Mice were vaccinated 2 times and then injected with tumor cells 2 weeks later. (B) Tumors were allowed to grow to 100 mm3, and 3.5 x 106 pfu/mouse in 25 ul of MVA, MVAmeso (meso) or MVAmesoA35Del (A35D) viruses were injected directly into tumors 3 times.

Fig 8

doi: https://doi.org/10.1371/journal.pone.0193131.g008