The osteogenic cell surface marker BRIL/IFITM5 is dispensable for bone development and homeostasis in mice
Femurs were analyzed by the three point bending test. Bones were loaded to failure at the midshaft and mechanical properties were measured from the resulting load vs. displacement curve. White bars represent WT groups and black bars represent KO groups. Values represent mean ± SD at each age point. Group size is n = 5 for all age points except 8m old KO where n = 3. Mechanical property measurements indicate no significant changes at any ages in both genders.