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New hydrazonoindolin-2-ones: Synthesis, exploration of the possible anti-proliferative mechanism of action and encapsulation into PLGA microspheres

Fig 4

A-549 human lung cancer cells were treated with 3.3 and 10 μM 7e over a time course from 2–48 h.

Caspase 3/7 activity was measured by a luminescence-based homogenous assay.

Fig 4

doi: https://doi.org/10.1371/journal.pone.0181241.g004