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Molecular features of influenza A (H1N1)pdm09 prevalent in Mexico during winter seasons 2012-2014

Fig 2

Analysis of detected substitutions at or beside antigenic sites of HA, of Mexican isolates from 2011–12 and 2013–14.

The analysis of substitutions at HA was made using sequence California/07/2009 as reference to establish the changes at the antigenic sites and in their neighboring positions. The antigenic sites are shaded and identified by colours. Blue is for Cb site, pink is for Sa site, Green is for Ca site and yellow is for Sb site. The amino acids in red represent changes detected in sequences of isolates from 2011–12 and white represent the changes detected in isolates from 2013–14.

Fig 2