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EnHERV: Enrichment analysis of specific human endogenous retrovirus patterns and their neighboring genes

Fig 5

Association heatmap between intragenic HERV and disease conditions.

A different intragenic HERV association pattern between cancer and auto-immune disease was identified. Intragenic HERVs were strongly associated with down-regulated genes in cancer. In contrast they are highly associated with up-regulated genes in immune cells under auto immune disease conditions.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0177119.g005