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Development of the full-length cDNA clones of two porcine epidemic diarrhea disease virus isolates with different virulence

Fig 4

Pathogenicity analyses of PEDV rBJ201C and rCHM2013.

(A) The average weight gain of piglets at the day of death or euthanasia at the final time points. (B) The clinical mental state scores of piglets of different groups. Criteria for evaluation: 0 = normal; 1 = mild lethargy (slow to move, head down); 2 = moderate lethargy (stands but tends to lie down); 3 = heavier lethargy (lie down, occasionally stand); 4 = severe lethargy (recumbent, moribund). (C) The survival rate of piglets of each group. Asterisk (*) indicates a significant difference between rBJ2011C and rCHM2013 (***P<0.001). Pound (#) indicates a significant difference between rBJ2011C and Mock (###P<0.001).

Fig 4

doi: https://doi.org/10.1371/journal.pone.0173998.g004