Wfs1 is expressed in dopaminoceptive regions of the amniote brain and modulates levels of D1-like receptors
Distribution of Wfs1, D1, and D5 proteins in the adult mouse brain, shown by immunohistochemistry on coronal sections. The sections are in anterio-posterior order from left to right. The detected proteins are indicated on the left side of the figure. Wfs1 is present in the cerebral cortex, in CA1 of hippocampus, CPu, Acb, Tu, amygdala, Rt, PV, VPM, hypothalamus and SNr (A-D). D1 is strongly present in CPu, Acb, Tu, hip, thalamus and SNr (E-H). D5 is present in CPu, Acb, S, hip, thalamus and SNc (I-L). Note that in Tu and SNr the distribution of D1, but not D5, is similar to Wfs1. For abbreviations, see list. Scale bar is 1 mm.