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Piphillin: Improved Prediction of Metagenomic Content by Direct Inference from Human Microbiomes

Fig 5

Comparison between Piphillin, PICRUSt and Tax4Fun.

(A) Spearman’s correlation coefficient against corresponding shotgun metagenomics results were compared. Spearman’s correlation coefficient was calculated for each sample and ranges are depicted as box and whisker plots as described in Fig 3. Green, human feces dataset; blue, human oral biopsy dataset; pink rat feces dataset; gray, hypersaline microbial mat dataset. (B) False positive rate, true positive rate and balanced accuracy of detecting significant differences between cancer and healthy human oral biopsy samples were compared.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0166104.g005