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Genetically Engineered Escherichia coli Nissle 1917 Synbiotics Reduce Metabolic Effects Induced by Chronic Consumption of Dietary Fructose

Fig 2

Effect of probiotic treatment on serum lipid profile.

(A) LDL, (B) HDL, (C) VLDL, (D) Cholesterol and (E) Triglycerides; on hepatic lipid profile (F) Cholesterol and (G) Triglycerides; (H) mRNA of Fatty acid synthase and (I) mRNA of Acyl Coenzyme A oxidase. Values are expressed as mean ± SEM (n = 5–6 each group). ***P≤ 0.001 compared with fructose control, @@@P ≤ 0.001 compared to fructose control, $ $ $ P ≤ 0.001, $ $ P ≤ 0.01 compared to EcN (pqq) group, ### ≤ 0.001. Values are expressed in mg/dl. F: Fructose.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0164860.g002