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A High-Throughput Screen Identifies 2,9-Diazaspiro[5.5]Undecanes as Inducers of the Endoplasmic Reticulum Stress Response with Cytotoxic Activity in 3D Glioma Cell Models

Fig 7

Compound 8 analogs reduce the viability of cancer cell lines.

CellTiter-Glo viability assay of glioma (U87-MG and LN-229), ovarian (IGROV-1 and HEY-A8) and colon (HT-29) cancer cell lines treated for 48 h with compound 8 analogs.

Fig 7

doi: https://doi.org/10.1371/journal.pone.0161486.g007