Advertisement
Browse Subject Areas
?

Click through the PLOS taxonomy to find articles in your field.

For more information about PLOS Subject Areas, click here.

< Back to Article

Lollipops in the Clinic: Information Dense Mutation Plots for Precision Medicine

Fig 1

Comparison of FGA plots from Lollipops tool (top) and cBioPortal (bottom).

Lollipops selects more informative axis labels and shows greater information density with the same plot size. Amino acid axis labels for domain start and stop positions, as well as exact marker locations, are clearly displayed for precision interpretation. In addition, lollipop labels are supported, and putative disordered regions (dark gray), low complexity regions (cyan), and signal peptides (orange) show additional structural information from Pfam without excessive detail.

Fig 1

doi: https://doi.org/10.1371/journal.pone.0160519.g001