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Proteotranscriptomic Analysis Reveals Stage Specific Changes in the Molecular Landscape of Clear-Cell Renal Cell Carcinoma

Fig 2

Correlation of differentially abundant proteins and respective gene expression levels in matched samples.

(A) There were 725 proteins identified which had 1764 corresponding probes in the corresponding transcriptomic data. Pearson's linear correlation coefficient was used to correlate normalized spectral count levels and RMA normalized microarray data in matched samples (94 samples). The average Pearson's linear correlation coefficient (r) was 0.157 (dotted line). (B) Distribution of r for just the 344 differentially abundant proteins, of which 318 were also measured in the corresponding transcriptomic study. The average r was 0.347 (dotted line).

Fig 2