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MicroRNA-3646 Contributes to Docetaxel Resistance in Human Breast Cancer Cells by GSK-3β/β-Catenin Signaling Pathway

Fig 7

RT-qPCR and Western blot analysis of β-catenin and P-β-catenin expression in MDA-MB-231/S and MDA-MB-231/Doc cells.

a Protein expression of β-catenin and P-β-catenin in MDA-MB-231/S and MDA-MB-231/Doc cells. b Protein expression of β-catenin and P-β-catenin in MDA-MB-231/S cells transfected with miR-3646 mimics, NC and blank control. c Protein expression of β-catenin and P-β-catenin protein in MDA-MB-231/Doc cells transfected with miR-3646 inhibitors, NC and blank control. d Relative mRNA expression of β-catenin in MDA-MB-231/S and MDA-MB-231/Doc cells (*P<0.05). e Relative mRNA expression of β-catenin in MDA-MB-231/S cells transfected with miR-3646 mimics, NC and blank control (*P<0.05). f Relative mRNA expression of β-catenin in MDA-MB-231/Doc cells transfected with miR-3646 inhibitors, NC and blank control (*P<0.05).

Fig 7

doi: https://doi.org/10.1371/journal.pone.0153194.g007