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Comparative Analysis of Stress Induced Gene Expression in Caenorhabditis elegans following Exposure to Environmental and Lab Reconstituted Complex Metal Mixture

Fig 6

Effect of metal exposure on C. elegans genes involved in apoptosis and innate immunity.

Apoptosis marker genes ape-1 and hus-1 and innate immunity modulators tir-1, clec-60, and bar-1 were analysed in C. elegans treated with the metal cocktail (MC) or waters from Lake Hornträsket (H) and Vombäcken stream at Björnås (B) and the exit to Vindelälven (V). One way analysis of variance (ANOVA) followed by Tukey’s post-test was used for multiple group comparison where * refers to p<0.01 as compared to control and # represents significant differences in between the sites H, B and V. The dotted line represents the expression level normalized to that of the control (K-medium prepared with Milli-Q water).

Fig 6

doi: https://doi.org/10.1371/journal.pone.0132896.g006