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Convection-Enhanced Delivery of Carboplatin PLGA Nanoparticles for the Treatment of Glioblastoma

Fig 1

Characterisation of carboplatin NP.

(A) Carboplatin NP show a consistent spherical shape, less than 200nm in size. Morphological analysis of the nanoparticles was conducted using TEM scaled at 200nm. (B) Approximately 100% of carboplatin is released within 24 hours. Release profile of carboplatin from nanoparticles was conducted by analysing platinum content by ICP-MS at defined timepoints.

Fig 1